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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Myrcludex B ： ウィキペディア英語版 Myrcludex B Myrcludex B is an experimental drug for the treatment of hepatitis B and D.〔 The first Phase IIa clinical trials with 40 patients concluded in 2014, finding that the drug was well tolerated and, as far as can be said with the limited data, effective against hepatitis B.〔 ==Mechanism of action== The hepatitis B virus uses its surface lipopeptide pre-S1 for docking to mature liver cells via their sodium/bile acid cotransporter (NTCP) and subsequently entering the cells. Myrcludex B is a synthetic N-acetylated pre-S1〔〔 that can also dock to NTCP, blocking the virus's entry mechanism.〔 The drug is also effective against hepatitis D because the hepatitis D virus is only infective in the presence of a hepatitis B virus infection.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Myrcludex B」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.